Description

4-Thiazolecarboxylicacid,5-Chloro-2-(Phenylethynyl)-,Ethylester(9Ci) CAS NO 425392-51-4 is a specialized heterocyclic building block featuring a thiazole core substituted with a chloro group and a phenylethynyl moiety. This compound is valued for its unique molecular architecture, which makes it a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological or electronic properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Material Science & Organic Electronics: Acts as a building block for conjugated molecules in the research of organic semiconductors, dyes, and photoactive materials.
• Chemical Synthesis: Employed in academic and industrial laboratories for method development and the construction of complex, functionalized thiazole derivatives.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Thiazolecarboxylicacid,5-Chloro-2-(Phenylethynyl)-,Ethylester(9Ci)
CAS No.	425392-51-4
Molecular Formula	C14H10ClNO2S
Molecular Weight	291.75 g/mol
Synonyms	Ethyl 5-Chloro-2-(phenylethynyl)thiazole-4-carboxylate; 5-Chloro-2-(2-phenylethynyl)-4-thiazolecarboxylic Acid Ethyl Ester; 4-Thiazolecarboxylic acid, 5-chloro-2-(2-phenylethynyl)-, ethyl ester; 425392-51-4; Ethyl 5-chloro-2-(phenylethynyl)-1,3-thiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of 4-Thiazolecarboxylicacid,5-Chloro-2-(Phenylethynyl)-,Ethylester(9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.