Description

Ethyl 5-Chloro-1,3-thiazole-4-carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its reactive carboxylate and halogenated thiazole functionalities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and advanced materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical research and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	Ethyl 5-Chloro-1,3-thiazole-4-carboxylate
CAS No.	425392-45-6
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	5-Chloro-1,3-thiazole-4-carboxylic acid ethyl ester; Ethyl 5-chloro-4-thiazolecarboxylate; 4-Carbethoxy-5-chlorothiazole; 5-Chloro-4-(ethoxycarbonyl)thiazole; Ethyl 5-chlorothiazole-4-carboxylate; 425392-45-6; 5-Chloro-thiazole-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-1,3-thiazole-4-carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP or ISO-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.