Description

n-(4-Methoxyphenyl)-5-Phenylthieno[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the research and development of novel therapeutic agents, particularly kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of targeted kinase inhibitors for cancer therapy research.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic assays and structure-activity relationship (SAR) studies.
• Academic Research: Employed in university and institutional labs for medicinal chemistry projects exploring novel heterocyclic scaffolds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions for clinical trial material production.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening for new drug candidates.

Basic Information

Product Name	n-(4-Methoxyphenyl)-5-Phenylthieno[2,3-D]Pyrimidin-4-Amine
CAS No.	423733-64-6
Molecular Formula	C19H15N3OS
Molecular Weight	333.41 g/mol
Synonyms	4-[(4-Methoxyphenyl)amino]-5-phenylthieno[2,3-d]pyrimidine; 5-Phenyl-N-(4-methoxyphenyl)thieno[2,3-d]pyrimidin-4-amine; Thieno[2,3-d]pyrimidin-4-amine, N-(4-methoxyphenyl)-5-phenyl-; 423733-64-6; 5-Phenyl-N-(p-methoxyphenyl)thieno[2,3-d]pyrimidin-4-amine; N-(4-Methoxyphenyl)-5-phenylthieno[2,3-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our n-(4-Methoxyphenyl)-5-Phenylthieno[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.