Description

2-[(5,6-Dimethylthieno[2,3-D]Pyrimidin-4-Yl)Sulfanyl]-1-(4-Fluorophenyl)Ethanone is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally complex building block for medicinal chemistry research and development, enabling the creation of targeted therapeutics. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on developing new drugs, particularly in oncology and other disease areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for developing biochemical probes and assay reagents.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	2-[(5,6-Dimethylthieno[2,3-D]Pyrimidin-4-Yl)Sulfanyl]-1-(4-Fluorophenyl)Ethanone
CAS No.	421578-46-3
Molecular Formula	C₁₆H₁₃FN₂OS₂
Molecular Weight	332.41 g/mol
Synonyms	1-(4-Fluorophenyl)-2-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)thio]ethanone; 2-((5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)thio)-1-(4-fluorophenyl)ethan-1-one; 4-[(4-Fluorobenzoyl)methylthio]-5,6-dimethylthieno[2,3-d]pyrimidine; CAS 421578-46-3
EINECS	Contact for details

Quality Control

Our 2-[(5,6-Dimethylthieno[2,3-D]Pyrimidin-4-Yl)Sulfanyl]-1-(4-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.