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[4-(2-Boc-Amino-Ethyl)-Phenyl]-Methanol CAS NO 421551-76-0


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CAS No.:421551-76-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[4-(2-Boc-Amino-Ethyl)-Phenyl]-Methanol is a high-purity, protected amino alcohol building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex pharmaceutical molecules and bioactive compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing peptide mimetics and other nitrogen-containing structures.

Application

  • Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
  • Peptidomimetic Synthesis: Used to create non-peptide compounds that mimic the structure and function of peptides, enhancing metabolic stability.
  • Linker Chemistry: Serves as a versatile spacer or linker in the construction of PROTACs (Proteolysis Targeting Chimeras) and antibody-drug conjugates (ADCs).
  • Agrochemical Research: Employed in the development of novel herbicides and pesticides with targeted modes of action.
  • Material Science: Acts as a monomer or functionalization agent for creating specialized polymers with tailored properties.
  • Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name [4-(2-Boc-Amino-Ethyl)-Phenyl]-Methanol
CAS No. 421551-76-0
Molecular Formula C15H23NO3
Molecular Weight 265.35 g/mol
Synonyms 4-(2-((tert-Butoxycarbonyl)amino)ethyl)benzyl alcohol; N-Boc-2-(4-(Hydroxymethyl)phenyl)ethan-1-amine; 2-(4-(Hydroxymethyl)phenyl)ethylcarbamic acid tert-butyl ester; tert-Butyl [2-(4-(hydroxymethyl)phenyl)ethyl]carbamate; Boc-NH-CH2CH2-C6H4-CH2OH; (4-{2-[(tert-Butoxycarbonyl)amino]ethyl}phenyl)methanol
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Quality Control

Our [4-(2-Boc-Amino-Ethyl)-Phenyl]-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥ 98.0%
Purity (HPLC, Area %) ≥ 99.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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