Description

Methyl 3-(5-Chlorothiophen-2-Yl)-2,2-Dimethylpropanoate is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its unique molecular structure, which incorporates both a chlorinated thiophene moiety and a hindered ester group, making it a versatile synthon in advanced chemical synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the chlorothiophene unit can contribute to biological activity.
• Material Science Research: Serves as a precursor for functionalized monomers or ligands in the development of specialty polymers and advanced materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing more complex heterocyclic compounds and fine chemicals.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in related manufacturing processes.

Basic Information

Product Name	Methyl 3-(5-Chlorothiophen-2-Yl)-2,2-Dimethylpropanoate
CAS No.	419565-61-0
Molecular Formula	C10H13ClO2S
Molecular Weight	232.72 g/mol
Synonyms	Methyl 3-(5-chloro-2-thienyl)-2,2-dimethylpropanoate; 2,2-Dimethyl-3-(5-chlorothiophen-2-yl)propanoic acid methyl ester; 3-(5-Chloro-2-thienyl)-2,2-dimethylpropionic acid methyl ester; 5-Chloro-2-thiophenepropanoic acid, 2,2-dimethyl-, methyl ester; Methyl 2,2-dimethyl-3-(5-chlorothiophen-2-yl)propionate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(5-Chlorothiophen-2-Yl)-2,2-Dimethylpropanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. All material is characterized and released against comprehensive specifications, which typically include identity confirmation by FT-IR and NMR, purity assessment by HPLC or GC, and control of key impurities. A Certificate of Analysis (COA) detailing the results for each batch is provided to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.