Description

1,2-Thiaphospholane-3-Carbonitrile,2-Ethoxy-3-Methyl-,2-Oxide,(2R,3R)-Rel-(9Ci) is a high-purity, stereochemically defined organophosphorus compound. This advanced chiral intermediate is critical for the synthesis of complex molecules where precise stereochemistry is required for biological activity. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereoisomers exhibit enhanced efficacy and selectivity.
• Catalyst Ligand Precursor: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Synthesis: Intermediate for the production of other high-value, stereochemically complex specialty chemicals.

Basic Information

Product Name	1,2-Thiaphospholane-3-Carbonitrile,2-Ethoxy-3-Methyl-,2-Oxide,(2R,3R)-Rel-(9Ci)
CAS No.	418815-49-3
Molecular Formula	C7H12NO3PS
Molecular Weight	221.22 g/mol
Synonyms	(2R,3R)-2-Ethoxy-3-methyl-1,2-thiaphospholane-3-carbonitrile 2-oxide; (2R,3R)-rel-2-Ethoxy-3-methyl-2-oxido-1,2-thiaphospholane-3-carbonitrile; 1,2-Thiaphospholane-3-carbonitrile, 2-ethoxy-3-methyl-, 2-oxide, (2R,3R)-rel-; 418815-49-3; (rel)-(2R,3R)-2-Ethoxy-3-methyl-1,2-thiaphospholane-3-carbonitrile 2-oxide; 2-Ethoxy-3-methyl-1,2-thiaphospholane-3-carbonitrile 2-oxide, (2R,3R)-rel-
EINECS	Contact for details

Quality Control

Our 1,2-Thiaphospholane-3-Carbonitrile,2-Ethoxy-3-Methyl-,2-Oxide,(2R,3R)-Rel-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and stereochemical composition is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.