Description

1H-Indole-3-Carboxylic Acid,6-(Trifluoromethyl)-,Methyl Ester is a high-value, fluorinated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an indole core and a trifluoromethyl group, makes it a versatile building block for creating compounds with enhanced biological activity and physicochemical properties. This specialty chemical is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in biochemical research to study enzyme mechanisms and protein interactions.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid,6-(Trifluoromethyl)-,Methyl Ester
CAS No.	415918-12-6
Molecular Formula	C11H8F3NO2
Molecular Weight	243.18 g/mol
Synonyms	Methyl 6-(trifluoromethyl)-1H-indole-3-carboxylate; 6-(Trifluoromethyl)-1H-indole-3-carboxylic acid methyl ester; 6-Trifluoromethylindole-3-carboxylic acid methyl ester; 1H-Indole-3-carboxylic acid, 6-(trifluoromethyl)-, methyl ester; Methyl 6-trifluoromethylindole-3-carboxylate; 415918-12-6; 6-CF3-1H-indole-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-3-Carboxylic Acid,6-(Trifluoromethyl)-,Methyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your research and development processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.