Description

4-(5-Bromothiophen-2-Yl)Benzonitrile is a high-purity organic building block featuring a brominated thiophene core linked to a benzonitrile moiety. This compound is valued for its versatility as a key synthetic intermediate in advanced material science and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the thiophene heterocycle for bioactivity.
• Material Science Research: Acts as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags due to its modifiable functional groups.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-(5-Bromothiophen-2-Yl)Benzonitrile
CAS No.	415718-60-4
Molecular Formula	C11H6BrNS
Molecular Weight	264.14 g/mol
Synonyms	4-(5-Bromo-2-thienyl)benzonitrile; 2-(4-Cyanophenyl)-5-bromothiophene; 5-Bromo-2-(4-cyanophenyl)thiophene; 4-(5-Bromothiophen-2-yl)benzonitrile; Benzonitrile, 4-(5-bromo-2-thienyl)-; 415718-60-4; 4-(5-Bromo-thiophen-2-yl)-benzonitrile
EINECS	Contact for details

Quality Control

Our production of 4-(5-Bromothiophen-2-Yl)Benzonitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.