Description

5-Chloro-1-Methyl-1H-Indole-3-Carboxaldehyde is a versatile and high-value indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both chloro and formyl substituents, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, receptor modulators, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive aldehyde and halogenated indole scaffold.
• Material Science: Employed in the creation of specialty polymers, dyes, and organic electronic materials where the indole core contributes to specific optical or electronic properties.
• Chemical Synthesis: Serves as a versatile starting material for further functionalization, including condensation reactions, nucleophilic additions, and transition-metal catalyzed cross-couplings.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies and the exploration of new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	5-Chloro-1-Methyl-1H-Indole-3-Carboxaldehyde
CAS No.	412284-65-2
Molecular Formula	C10H8ClNO
Molecular Weight	193.63 g/mol
Synonyms	5-Chloro-1-methylindole-3-carboxaldehyde; 5-Chloro-1-methyl-1H-indole-3-carbaldehyde; 1-Methyl-5-chloroindole-3-carboxaldehyde; 3-Formyl-5-chloro-1-methylindole; 412284-65-2; 5-Chloro-1-methylindole-3-aldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-1-Methyl-1H-Indole-3-Carboxaldehyde is manufactured and tested under strict quality management protocols to ensure consistency and purity. Our standard grade typically meets a high purity specification, verified by advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening the primary container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.