Description

2-(Prop-2-Yn-1-Yl)-1,2,3,4-Tetrahydroisoquinoline-1,3-Dione CAS NO 410538-30-6 is a specialized heterocyclic building block featuring a tetrahydroisoquinolinedione core functionalized with a propargyl group. This compound is valued for its unique molecular scaffold, which serves as a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor for click chemistry reactions, utilizing the alkyne moiety for Huisgen cycloaddition to create triazole-linked compounds.
• Material Science: Investigated as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and protein interactions.

Basic Information

Product Name	2-(Prop-2-Yn-1-Yl)-1,2,3,4-Tetrahydroisoquinoline-1,3-Dione
CAS No.	410538-30-6
Molecular Formula	C₁₂H₉NO₂
Molecular Weight	199.21 g/mol
Synonyms	2-Propargyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione; 2-(Prop-2-ynyl)-1,2,3,4-tetrahydro-1,3-isoquinolinedione; 1,3-Dioxo-2-(2-propynyl)-1,2,3,4-tetrahydroisoquinoline; N-Propargyl-1,3-dioxoisoindoline; 2-(2-Propynyl)-1H-isoindole-1,3(2H)-dione; Tetrahydroisoquinolinedione propargyl derivative; Propargyl-substituted tetrahydrophthalimide
EINECS	Contact for details

Quality Control

Our 2-(Prop-2-Yn-1-Yl)-1,2,3,4-Tetrahydroisoquinoline-1,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.