Description

tert-Butyl ((Diphenylphosphoryl)-Methyl)Sulfonylcarbamate is a specialized organophosphorus compound designed for advanced synthetic chemistry applications. This high-value intermediate is crucial for researchers and manufacturers developing novel pharmaceuticals and agrochemicals, where precise molecular construction is paramount. Its unique structure, featuring both sulfonylcarbamate and phosphine oxide functionalities, makes it an essential building block for medicinal chemists and process development scientists.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators requiring specific phosphorus-containing motifs.
• Ligand Synthesis: Serves as a starting material for the preparation of sophisticated chiral or bidentate ligands used in asymmetric catalysis.
• Peptidomimetic Chemistry: Employed in the construction of peptide analogs and protease inhibitors where the sulfonylcarbamate group mimics a peptide bond.
• Material Science: Investigated for incorporation into specialty polymers and advanced materials with specific electronic or surface properties.
• Cross-Coupling Reactions: Acts as a functionalized reagent in palladium-catalyzed cross-coupling reactions to introduce complex molecular fragments.

Basic Information

Product Name	tert-Butyl ((Diphenylphosphoryl)-Methyl)Sulfonylcarbamate
CAS No.	410529-86-1
Molecular Formula	C18H22NO5PS
Molecular Weight	395.41 g/mol
Synonyms	tert-Butyl N-[(diphenylphosphoryl)methyl]sulfonylcarbamate; Carbamic acid, N-[(diphenylphosphinyl)methyl]sulfonyl-, 1,1-dimethylethyl ester; BOC-Protected Phosphorylmethylsulfonylcarbamate; (Diphenylphosphoryl)methylsulfonylcarbamic acid tert-butyl ester; tert-Butyl [(diphenylphosphoryl)methyl]sulfamoylcarbamate; tert-Butyl sulfonyl((diphenylphosphoryl)methyl)carbamate; N-(tert-Butoxycarbonyl)-N-[(diphenylphosphoryl)methyl]sulfonamide
EINECS	Contact for details

Quality Control

Our tert-Butyl ((Diphenylphosphoryl)-Methyl)Sulfonylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.