Description

Apramycin Sulfate is a water-soluble aminoglycoside antibiotic derived from *Streptomyces tenebrarius*. This compound is valued for its broad-spectrum activity against Gram-negative bacteria and specific Gram-positive organisms, making it a critical tool in veterinary medicine and research. It is primarily utilized by manufacturers in the animal health sector, as well as by research institutions and pharmaceutical development laboratories focused on antibacterial agents.

Application

• Veterinary Pharmaceutical Formulations: A key active ingredient in injectable solutions, powders, and premixes for the treatment of bacterial infections in livestock, poultry, and companion animals.
• Animal Feed Additive: Used at therapeutic or sub-therapeutic levels to prevent and control enteric diseases, promoting growth and feed efficiency.
• Microbiological Research: Serves as a selective agent in culture media and as a tool for studying bacterial resistance mechanisms within the aminoglycoside class.
• API Intermediate: Employed as a starting material or intermediate in the synthesis of more complex antibiotic formulations and novel derivatives.
• Laboratory Standard: Used as a certified reference standard for quality control and analytical method development in regulatory and quality assurance labs.

Basic Information

Product Name	Apramycin Sulfate
CAS No.	410097-64-2
Molecular Formula	C21H41N5O11 • xH2SO4
Molecular Weight	539.58 g/mol (for free base)
Synonyms	Apramycin Sulphate; Nebramycin II; EL-857/820; Antibiotic EL 857; 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-(3-deoxy-4-C-methyl-3-methylamino-β-L-arabinopyranosyl)-2-deoxystreptamine sulfate; Apralan (Veterinary Brand Name)
EINECS	Contact for details

Quality Control

Our Apramycin Sulfate is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for veterinary and research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles. We can supply material compliant with relevant pharmacopeial monographs upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
pH (1% Solution)	4.0 - 6.0
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.