Description

1(2H)-Isoquinolinone,5-Fluoro-(9Ci) CAS NO 410086-25-8 is a high-purity fluorinated isoquinolinone derivative, a crucial advanced intermediate in modern synthetic chemistry. This compound matters for its role as a versatile building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom is strategically introduced to modulate biological activity and metabolic stability. Pharmaceutical research and development teams, as well as agrochemical innovators, need this specific intermediate to synthesize next-generation compounds targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorinated isoquinolinone core contributes to efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty chemicals, dyes, and functional organic materials with specific electronic or photophysical properties.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs) focused on heterocyclic and fluorine chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	1(2H)-Isoquinolinone,5-Fluoro-(9Ci)
CAS No.	410086-25-8
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	5-Fluoro-1(2H)-isoquinolinone; 5-Fluoro-2H-isoquinolin-1-one; 5-Fluoro-1,2-dihydroisoquinolin-1-one; 5-Fluoro-1-isoquinolinol; 5-Fluoro-1-hydroxyisoquinoline; 5-Fluoroisoquinolin-1(2H)-one; 5-Fluoro-1,2-dihydro-isoquinolin-1-one; 5-Fluoro-1-isoquinolinone
EINECS	Contact for details

Quality Control

Our 1(2H)-Isoquinolinone,5-Fluoro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.