Description

6-tert-Butyl-2-(Furan-2-Carboxamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylic Acid is a high-purity, complex heterocyclic carboxylic acid derivative that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular architecture, which combines a tetrahydrobenzo[b]thiophene core with furan and tert-butyl substituents, making it a versatile building block for pharmaceutical research and fine chemical development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe: Serves as a scaffold or precursor for designing molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or organic electronic materials due to its fused ring system.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Custom Synthesis & Scale-Up: Supplied for process optimization and pilot-scale production under cGMP or ISO standards for clinical trial material.

Basic Information

Product Name	6-tert-Butyl-2-(Furan-2-Carboxamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylic Acid
CAS No.	407587-33-1
Molecular Formula	C₂₀H₂₃NO₄S
Molecular Weight	373.47 g/mol
Synonyms	6-tert-Butyl-2-[(furan-2-carbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid; 2-[(Furan-2-carbonyl)amino]-6-(tert-butyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid; 6-tert-Butyl-2-(2-furoylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic Acid; Furan-2-carboxamide, N-[6-(1,1-dimethylethyl)-3-carboxy-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-; CAS 407587-33-1
EINECS	Contact for details

Quality Control

Our production of 6-tert-Butyl-2-(Furan-2-Carboxamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylic Acid adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support custom synthesis under ISO 9001 guidelines with optional cGMP compliance for advanced pharmaceutical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.