Description

(S)-1-Chloro-3-Phenylpropan-2-Ol is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its defined stereochemistry makes it a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals requiring specific enantiomeric purity. This compound is essential for research and production in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of β-blockers, antidepressants, and other cardiovascular or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the manufacture of chiral pesticides and herbicides where stereochemistry affects biological activity.
• Asymmetric Synthesis: Serves as a versatile starting material or reagent in catalytic asymmetric reactions for constructing complex molecular architectures.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, fragrances, and liquid crystals.
• Academic & Industrial Research: Valuable compound for method development in organic synthesis and medicinal chemistry research.
• Peptide Mimetics: Useful in the preparation of peptidomimetic compounds for drug discovery programs.

Basic Information

Product Name	(S)-1-Chloro-3-Phenylpropan-2-Ol
CAS No.	406945-51-5
Molecular Formula	C9H11ClO
Molecular Weight	170.64 g/mol
Synonyms	(S)-1-Chloro-3-phenyl-2-propanol; (S)-3-Phenyl-2-chloro-1-propanol; (S)-2-Chloro-1-phenyl-3-propanol; (S)-Phenylpropanol Chloride; (S)-Chlorohydrin precursor; (S)-Epichlorohydrin phenyl adduct; (S)-β-Chloro-α-hydroxypropylbenzene; (S)-1-Chloro-3-phenylpropan-2-ol
EINECS	Contact for details

Quality Control

We supply (S)-1-Chloro-3-Phenylpropan-2-Ol in high-purity grades suitable for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as chiral purity (enantiomeric excess), chemical purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.