Description

7-Fluoro-1,2,3,4-Tetrahydro-Isoquinoline is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a tetrahydroisoquinoline scaffold with a fluorine substituent, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and fluorescent markers due to its electron-donating and modifying capabilities.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	7-Fluoro-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	406923-91-9
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	7-Fluoro-1,2,3,4-tetrahydroisoquinoline; 7-Fluoro-THIQ; 7-Fluoro-3,4-dihydro-1H-isoquinoline; 1,2,3,4-Tetrahydro-7-fluoro-isoquinoline; 7-Fluoro-1,2,3,4-tetrahydroisoquinoline; 7-Fluoro-1,2,3,4-tetrahydro-isoquinoline; 7-Fluoro-3,4-dihydroisoquinoline
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.