Description

Isoquinoline, 5-Fluoro-1,2,3,4-Tetrahydro- (9Ci) is a fluorinated tetrahydroisoquinoline derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its unique scaffold, which is integral to the development of novel pharmacologically active compounds. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential drug candidates targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of new active pharmaceutical ingredients (APIs), especially in neurological and psychiatric drug discovery.
• Medicinal Chemistry Research: Used as a privileged scaffold in structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: Employed in fundamental organic synthesis research and process development for complex molecule manufacturing.

Basic Information

Product Name	Isoquinoline, 5-Fluoro-1,2,3,4-Tetrahydro- (9Ci)
CAS No.	406923-64-6
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	5-Fluoro-1,2,3,4-tetrahydroisoquinoline; 5-Fluoro-1,2,3,4-THQ; 5-Fluoro-THIQ; 5-F-THIQ; 5-Fluoro-3,4-dihydro-1H-isoquinoline; 5-Fluorotetrahydroisoquinoline; 5-Fluoro-1,2,3,4-tetrahydroisoquinoline (9CI)
EINECS	Contact for details

Quality Control

Our Isoquinoline, 5-Fluoro-1,2,3,4-Tetrahydro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.