Description

1H-Benzimidazole-1-Acetaldehyde is a versatile and high-value heterocyclic building block, specifically a functionalized benzimidazole derivative. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its reactive aldehyde group, which allows for further derivatization and incorporation into complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting various enzyme families and receptors.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and plant growth regulators that leverage the benzimidazole scaffold.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Polymer & Material Science: Acts as a monomer or functionalizing agent for creating polymers with specific electronic or binding properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific benzimidazole-based structures.

Basic Information

Product Name	1H-Benzimidazole-1-Acetaldehyde
CAS No.	405174-42-7
Molecular Formula	C9H8N2O
Molecular Weight	160.18 g/mol
Synonyms	1H-Benzimidazole-1-acetaldehyde; 1-(2-Oxoethyl)-1H-benzimidazole; 2-(1H-Benzimidazol-1-yl)acetaldehyde; 1H-Benzimidazole-1-ethanal; Benzimidazole-1-acetaldehyde; N-(2-Oxoethyl)benzimidazole; 1-Carbaldehyde-1H-benzimidazole (incorrect but common search term); 1-(Formylmethyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-1-Acetaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications. We support cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.