Description

7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carboxylicacid,2-Hydroxy-,(1R,2R,4R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic lactone derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique oxabicyclic structure and defined stereochemistry make it an invaluable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those requiring rigid, polycyclic frameworks.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where specific stereochemistry influences biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Material Science Monomer: Potential use in creating specialized polymers with unique thermal or mechanical properties derived from its strained bicyclic structure.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for stereoselective transformations.
• Fine Chemical Synthesis: Building block for fragrances, flavors, and other high-value specialty chemicals requiring specific enantiomeric purity.

Basic Information

Product Name	7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carboxylicacid,2-Hydroxy-,(1R,2R,4R)-Rel-(9Ci)
CAS No.	405162-90-5
Molecular Formula	C7H8O4
Molecular Weight	156.14 g/mol
Synonyms	(1R,2R,4R)-rel-2-Hydroxy-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid; (1R,2R,4R)-2-Hydroxy-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 7-Oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 2-hydroxy-, (1R,2R,4R)-rel-; Bicyclic Lactone Acid Derivative; 2-Hydroxy-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic Acid (rel-(1R,2R,4R)-form); Oxanorbornene Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our 7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carboxylicacid,2-Hydroxy-,(1R,2R,4R)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and chiral purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified for the specific grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.