Description

5-Thiazolemethanol,2-Ethyl-4-(Trifluoromethyl)-(9Ci) is a high-value, functionalized thiazole derivative, identified by CAS NO 405103-63-1. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Research: Used as a building block for developing new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and trifluoromethyl motifs.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science & OLEDs: Potential monomer or additive for creating advanced polymers and organic light-emitting diodes (OLEDs) due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in medicinal chemistry for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	5-Thiazolemethanol,2-Ethyl-4-(Trifluoromethyl)-(9Ci)
CAS No.	405103-63-1
Molecular Formula	C7H8F3NOS
Molecular Weight	211.21 g/mol
Synonyms	2-Ethyl-4-(trifluoromethyl)-1,3-thiazole-5-methanol; (2-Ethyl-4-(trifluoromethyl)thiazol-5-yl)methanol; 5-Thiazolemethanol, 2-ethyl-4-(trifluoromethyl)-; 2-Ethyl-4-trifluoromethylthiazole-5-methanol; 4-(Trifluoromethyl)-2-ethyl-5-thiazolemethanol; 2-Ethyl-4-(trifluoromethyl)-5-thiazolemethanol; 5-(Hydroxymethyl)-2-ethyl-4-(trifluoromethyl)thiazole
EINECS	Contact for details

Quality Control

Our production of 5-Thiazolemethanol,2-Ethyl-4-(Trifluoromethyl)-(9Ci) adheres to stringent ISO 9001 quality management principles. Every batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay purity and impurity profiles. Specifications can be aligned with cGMP requirements for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.