Description

2-Propenoic Acid, 3-[4-[[[2-(1H-Indol-3-Yl)Ethyl]Amino]Methyl]Phenyl]-, Methyl Ester, (2E)- is a specialized acrylate derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both an indole moiety and a reactive acrylate ester, makes it a valuable building block for constructing complex molecules with specific biological or material properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Building block for developing new pesticides, herbicides, or plant growth regulators with enhanced efficacy.
• Bioconjugation & Probe Synthesis: Used in creating fluorescent probes, affinity labels, or other biochemical tools due to its reactive acrylate group.
• Material Science: Monomer or cross-linking agent in the development of specialty polymers, coatings, or hydrogels with tailored properties.
• Chemical Biology: Intermediate for synthesizing enzyme inhibitors or receptor modulators for research purposes.
• Academic & Contract Research: Essential reagent for exploratory synthetic chemistry in university and CRO laboratories.

Basic Information

Item	Details
Product Name	2-Propenoic Acid, 3-[4-[[[2-(1H-Indol-3-Yl)Ethyl]Amino]Methyl]Phenyl]-, Methyl Ester, (2E)-
CAS No.	404951-55-9
Molecular Formula	C21H22N2O2
Molecular Weight	334.42 g/mol
Synonyms	(2E)-3-[4-[[[2-(1H-Indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenoic acid methyl ester; Methyl (2E)-3-[4-[[2-(1H-indol-3-yl)ethylamino]methyl]phenyl]acrylate; (E)-Methyl 3-(4-((2-(1H-indol-3-yl)ethylamino)methyl)phenyl)acrylate; Acrylic acid derivative CAS 404951-55-9; Indole-based acrylate ester
EINECS	Contact for details

Quality Control

Every batch of 2-Propenoic Acid, 3-[4-[[[2-(1H-Indol-3-Yl)Ethyl]Amino]Methyl]Phenyl]-, Methyl Ester, (2E)- is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant analytical methods is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.