Description

2-Propenamide, n-Hydroxy-3-[4-[[(2-Hydroxyethyl)[2-(1H-Indol-3-Yl)Ethyl]Amino]Methyl]Phenyl]-, (2E)- is a specialized, high-purity synthetic intermediate featuring a unique molecular architecture combining acrylamide, hydroxyphenyl, and indole moieties. This compound matters for its role as a key building block in the synthesis of advanced materials and biologically active molecules, offering precise reactivity for targeted chemical modifications. It is primarily needed by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and advanced polymer sectors for developing novel therapeutic agents, crop protection chemicals, and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways, leveraging its indole and reactive acrylamide groups.
• Agrochemical Research: Used in developing next-generation pesticides and plant growth regulators where its specific structure can impart unique biological activity.
• Polymer Science & Advanced Materials: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties like UV-responsiveness or specific molecular recognition.
• Bioconjugation & Probe Development: Utilized in life sciences research for labeling biomolecules (proteins, nucleic acids) due to its photoreactive or click-chemistry compatible functional groups.
• Chemical Biology Tool: Employed in probe molecules to study enzyme function or protein-protein interactions within complex biological systems.
• Dye & Pigment Intermediate: Potential use in synthesizing complex organic dyes and pigments for high-performance imaging or display technologies.

Basic Information

Item	Details
Product Name	2-Propenamide, n-Hydroxy-3-[4-[[(2-Hydroxyethyl)[2-(1H-Indol-3-Yl)Ethyl]Amino]Methyl]Phenyl]-, (2E)-
CAS No.	404951-53-7
Molecular Formula	C23H27N3O3
Molecular Weight	393.48 g/mol
Synonyms	(2E)-N-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]acrylamide; N-Hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl}phenyl)acrylamide; Hydroxyphenylacrylamide-indole derivative; Acrylamide-based indole derivative; Photoaffinity labeling intermediate; SAHA-related hybrid compound; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management protocols. We employ state-of-the-art analytical techniques including HPLC, NMR, and Mass Spectrometry to verify identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), residual solvents, and other critical parameters is provided with each shipment to ensure it meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.