Description

6-tert-Butyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetically derived organic salt with the CAS number 404576-48-3. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis, valued for its defined stereochemistry and reactivity. It is primarily required by R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Research: Building block for developing new generation herbicides and plant growth regulators with enhanced efficacy.
• Organic Synthesis Reagent: Used in the construction of complex nitrogen-containing heterocycles for material science and catalysis.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Ligand Synthesis: Intermediate for creating novel chiral ligands used in asymmetric catalysis.
• Academic & Industrial R&D: Fundamental research compound for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	6-tert-Butyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	404576-48-3
Molecular Formula	C₁₃H₂₀ClN
Molecular Weight	225.76 g/mol
Synonyms	6-tert-Butyl-1,2,3,4-tetrahydroisoquinoline HCl; 6-(tert-Butyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-6-(1,1-dimethylethyl)isoquinoline hydrochloride; 6-tert-Butyl-THIQ hydrochloride; 6-tert-Butyl-1,2,3,4-THIQ·HCl; 6-tert-Butyl-3,4-dihydro-1H-isoquinoline hydrochloride; 404576-48-3
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.