Description

5-(Trifluoromethoxy)Indolin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique indolinone core and trifluoromethoxy substituent. This compound is essential for medicinal chemistry research and development, offering a versatile building block for creating novel bioactive molecules. It is primarily sought after by R&D teams and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	5-(Trifluoromethoxy)Indolin-2-One
CAS No.	403853-48-5
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	5-(Trifluoromethoxy)-2-indolinone; 5-(Trifluoromethoxy)indolin-2-one; 2-Oxo-5-(trifluoromethoxy)indoline; 5-(Trifluoromethoxy)-1,3-dihydro-2H-indol-2-one; 403853-48-5; 5-Trifluoromethoxy-2-indolinone; 5-Trifluoromethoxyindolin-2-one
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethoxy)Indolin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.