Description

1H-Inden-1-Ol, 3-Amino-2,3-Dihydro-, (1S,3R)- (9Ci) is a chiral, amino-substituted indanol derivative, a high-value building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it a critical intermediate for constructing complex molecular architectures with high enantiomeric purity. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Agrochemical Synthesis: Used in the research and production of advanced, stereochemically-defined pesticides and herbicides.
• Material Science Research: Investigated as a monomer or building block for specialty polymers and advanced organic materials.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1H-Inden-1-Ol, 3-Amino-2,3-Dihydro-, (1S,3R)- (9Ci)
CAS No.	403672-05-9
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(1S,3R)-3-Amino-2,3-dihydro-1H-inden-1-ol; (1S,3R)-3-Aminoindan-1-ol; 3-Amino-2,3-dihydro-1H-inden-1-ol, (1S,3R)-; (1S,3R)-1-Hydroxy-3-aminoindane; cis-3-Aminoindan-1-ol; Aminoindanol; Chiral Aminoindanol Derivative
EINECS	Contact for details

Quality Control

We supply 1H-Inden-1-Ol, 3-Amino-2,3-Dihydro-, (1S,3R)- (9Ci) in high-purity grades suitable for demanding synthetic applications. Our products undergo rigorous quality testing, including chiral purity analysis (HPLC, Chiral GC), to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess, and impurity profile is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.