Description

N'-[(E)-(4-Hydroxy-3-Methoxyphenyl)Methylidene]-3-(5-Methylthiophen-2-Yl)-1H-Pyrazole-5-Carbohydrazide is a sophisticated heterocyclic compound featuring a pyrazole core linked to a methoxyphenyl hydrazone moiety, representing a high-value chemical building block. This compound matters for its role as a key intermediate in advanced organic synthesis, particularly in the development of novel pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and the development of new functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Agrochemical Development: Acts as a building block for creating novel active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Employed in the design and creation of molecular probes for studying biological processes.
• Material Science Research: Investigated for its potential in creating organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting discovery and development projects for global clients.

Basic Information

Product Name	N'-[(E)-(4-Hydroxy-3-Methoxyphenyl)Methylidene]-3-(5-Methylthiophen-2-Yl)-1H-Pyrazole-5-Carbohydrazide
CAS No.	403650-85-1
Molecular Formula	C17H16N4O3S
Molecular Weight	356.40 g/mol
Synonyms	3-(5-Methyl-2-thienyl)-1H-pyrazole-5-carboxylic acid [(E)-2-(4-hydroxy-3-methoxyphenyl)methylene]hydrazide; (E)-N'-(4-Hydroxy-3-methoxybenzylidene)-3-(5-methylthiophene-2-carbonyl)hydrazinecarboxamide; 403650-85-1; Pyrazole-thiophene hydrazone derivative; Vanillin isonicotinoyl hydrazone analog (thiophene variant); 5-Methyl-2-thienyl pyrazole carbohydrazide
EINECS	Contact for details

Quality Control

Our N'-[(E)-(4-Hydroxy-3-Methoxyphenyl)Methylidene]-3-(5-Methylthiophen-2-Yl)-1H-Pyrazole-5-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.