Description

2-(4-Iodobutyl)-5,5-Dimethyl-1,3-Dioxane CAS NO 402480-06-2 is a specialized organic intermediate featuring a protected aldehyde functionality and a reactive iodoalkyl chain. This compound is valued for its dual reactivity, serving as a versatile building block in complex organic synthesis and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring protected aldehyde precursors and carbon chain elongation.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive iodide for coupling reactions.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and dendrimers where controlled chain growth is essential.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions (e.g., Negishi, Stille) to form new carbon-carbon bonds.
• Protecting Group Chemistry: The 1,3-dioxane moiety acts as a protecting group for aldehydes, which can be deprotected under mild acidic conditions.

Basic Information

Product Name	2-(4-Iodobutyl)-5,5-Dimethyl-1,3-Dioxane
CAS No.	402480-06-2
Molecular Formula	C10H19IO2
Molecular Weight	298.16 g/mol
Synonyms	5,5-Dimethyl-2-(4-iodobutyl)-1,3-dioxane; 1,3-Dioxane, 2-(4-iodobutyl)-5,5-dimethyl-; 2-(4-Iodobutyl)-5,5-dimethyl-1,3-dioxacyclohexane; 4-(5,5-Dimethyl-1,3-dioxan-2-yl)butyl iodide; (4-Iodobutyl)acetaldehyde dimethyl acetal (cyclic form); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Standard quality control includes identification by spectroscopic methods (IR, NMR), purity assessment by HPLC or GC, and specific tests for residual solvents and heavy metals where applicable. Certificates of Analysis (COA) documenting all test results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.