Description

Bicyclo[2.2.1]Heptane-1,2-Diamine, 3,3-Dimethyl-, (1S,2S,4S)- (9Ci) is a high-purity, chiral diamine building block characterized by its rigid bicyclic framework. This compound is of significant commercial interest due to its utility as a sophisticated ligand and catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel chiral architectures.

Application

• Asymmetric Catalysis: Serves as a key precursor for chiral ligands and catalysts used in enantioselective hydrogenation, cyclopropanation, and other C-C bond-forming reactions.
• Pharmaceutical Intermediates: Employed in the synthesis of active pharmaceutical ingredients (APIs) requiring high stereochemical purity, particularly in neurology and oncology drug candidates.
• Chiral Resolution Agents: Used to separate enantiomers of racemic mixtures in analytical and preparative-scale chromatography.
• Advanced Material Synthesis: Acts as a monomer or cross-linking agent in the development of chiral polymers and resins with specific optical or mechanical properties.
• Agrochemical Research: Utilized in creating novel, stereochemically defined active ingredients for herbicides and pesticides.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-1,2-Diamine, 3,3-Dimethyl-, (1S,2S,4S)- (9Ci)
CAS No.	401929-50-8
Molecular Formula	C9H18N2
Molecular Weight	154.25 g/mol
Synonyms	(1S,2S,4S)-3,3-Dimethylbicyclo[2.2.1]heptane-1,2-diamine; (1S,2S,4S)-3,3-Dimethylnorbornane-1,2-diamine; (1S,2S,4S)-3,3-Dimethyl-2-aminonorbornan-1-amine; endo-3,3-Dimethylbicyclo[2.2.1]heptane-1,2-diamine; Chiral Norbornane Diamine Derivative; 401929-50-8; (1S,2S,4S)-3,3-Dimethyl-2,3-dihydro-1H-cyclopenta[a]naphthalene-1,2-diamine (incorrect but sometimes indexed)
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-1,2-Diamine, 3,3-Dimethyl-, (1S,2S,4S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC/MS. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.