Description

(3Z)-5-Ethyl-1H-Indole-2,3-Dione 3-Thiosemicarbazone is a specialized heterocyclic organic compound belonging to the class of isatin thiosemicarbazones. This compound matters as a versatile chemical intermediate and a key scaffold in medicinal chemistry research, particularly valued for its potential biological activity. It is needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, as well as by fine chemical manufacturers producing advanced intermediates for agrochemicals and other high-value applications.

Application

• Pharmaceutical Research & Development: Serves as a crucial synthetic intermediate and a pharmacophore in the discovery of new drug candidates, particularly for anticancer, antiviral, and antimicrobial agents.
• Medicinal Chemistry: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Biochemical Research: Employed in biochemical assays to study enzyme inhibition, particularly targeting enzymes like ribonucleotide reductase.
• Fine Chemical Synthesis: Acts as a key building block for the synthesis of more complex heterocyclic compounds and functional materials.
• Agrochemical Intermediates: Potential use in the synthesis of novel active ingredients for crop protection products.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	(3Z)-5-Ethyl-1H-Indole-2,3-Dione 3-Thiosemicarbazone
CAS No.	401899-98-7
Molecular Formula	C11H12N4OS
Molecular Weight	248.30 g/mol
Synonyms	5-Ethylisatin 3-thiosemicarbazone; (Z)-5-Ethyl-2,3-dioxoindoline-3-thiosemicarbazone; 5-Ethyl-1H-indole-2,3-dione 3-thiosemicarbazone; 5-Ethylisatin-β-thiosemicarbazone; 401899-98-7; 5-Ethyl-1H-indole-2,3-dione thiosemicarbazone; (3Z)-5-Ethyl-1H-indole-2,3-dione 3-(thiosemicarbazone)
EINECS	Contact for details

Quality Control

Our (3Z)-5-Ethyl-1H-Indole-2,3-Dione 3-Thiosemicarbazone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.