Description

4-Chloro-1-(Piperazin-1-Yl)Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its fused isoquinoline and piperazine heterocyclic structure. This compound matters as a critical building block in medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Serves as a functionalized intermediate for constructing more complex heterocyclic compounds in organic synthesis.
• Biochemical Tool Compound: Potential use in the development of probes for studying biological pathways and enzyme inhibition.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	4-Chloro-1-(Piperazin-1-Yl)Isoquinoline
CAS No.	401567-94-0
Molecular Formula	C13H14ClN3
Molecular Weight	247.72 g/mol
Synonyms	4-Chloro-1-(piperazin-1-yl)isoquinoline; 4-Chloro-1-piperazinylisoquinoline; 1-(4-Chloroisoquinolin-1-yl)piperazine; 401567-94-0; 4-Chloro-1-piperazin-1-ylisoquinoline; 4-Chloro-1-(1-piperazinyl)isoquinoline; 1-Piperazine, 1-(4-chloro-1-isoquinolinyl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(Piperazin-1-Yl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.