Description

5-(2-Methyl-1,3-thiazol-4-yl)-2-thiophenecarboxylic acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its unique thiazole-thiophene scaffold.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as conductive polymers and organic semiconductors, due to its conjugated system.
• Ligand Synthesis: Utilized in coordination chemistry for the preparation of specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Incorporated into molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	5-(2-Methyl-1,3-thiazol-4-yl)-2-thiophenecarboxylic Acid
CAS No.	400715-45-9
Molecular Formula	C9H7NO2S2
Molecular Weight	225.29 g/mol
Synonyms	4-(2-Methyl-4-thiazolyl)-2-thiophenecarboxylic Acid; 2-Thiophenecarboxylic acid, 5-(2-methyl-4-thiazolyl)-; 5-(2-Methyl-1,3-thiazol-4-yl)thiophene-2-carboxylic acid; 5-(2-Methylthiazol-4-yl)thiophene-2-carboxylic Acid; 5-(2-Methyl-4-thiazolyl)-2-thiophenecarboxylic Acid; 5-(2-Methyl-1,3-thiazol-4-yl)-2-thiophene carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(2-Methyl-1,3-thiazol-4-yl)-2-thiophenecarboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.