Description

3-(4-Chlorophenyl)-2-Cyclohexyl-1-Oxo-1,2,3,4-Tetrahydro-4-Isoquinolinecarboxylic Acid is a high-purity, synthetically derived organic compound serving as a critical intermediate in advanced pharmaceutical research and development. Its complex molecular architecture, featuring fused isoquinoline and cyclohexyl motifs, makes it a valuable scaffold for medicinal chemists exploring novel therapeutic agents. This compound is primarily utilized by R&D laboratories and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex molecules for biological evaluation.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Tool Compound: Potential use in probing specific biological pathways or enzyme interactions in preclinical research.

Basic Information

Product Name	3-(4-Chlorophenyl)-2-Cyclohexyl-1-Oxo-1,2,3,4-Tetrahydro-4-Isoquinolinecarboxylic Acid
CAS No.	400073-91-8
Molecular Formula	C22H22ClNO3
Molecular Weight	383.87 g/mol
Synonyms	4-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-3-(4-chlorophenyl)-2-cyclohexyl-1-oxo-; 2-Cyclohexyl-3-(4-chlorophenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid; 3-(p-Chlorophenyl)-2-cyclohexyl-1-oxo-1,2,3,4-tetrahydro-4-isoquinolinecarboxylic acid; CAS 400073-91-8; Tetrahydroisoquinolinecarboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)-2-Cyclohexyl-1-Oxo-1,2,3,4-Tetrahydro-4-Isoquinolinecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results for that batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.