Description

(S1)-Methoxy-3-Heptanethiol CAS NO 400052-49-5 is a high-purity, chiral thiol compound featuring a methoxy group on the heptane backbone. This specific stereochemistry and functional group combination make it a valuable chiral building block and ligand precursor in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications requiring precise molecular control. The compound's utility extends to asymmetric catalysis and the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in enantioselective synthesis to produce single-isomer compounds.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals, fragrances, and agrochemicals.
• Material Science Research: Used in the development of novel polymers or functional materials where the thiol group enables specific surface modifications or cross-linking.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry and process development within contract research organizations (CROs) and chemical companies.

Basic Information

Product Name	(S1)-Methoxy-3-Heptanethiol
CAS No.	400052-49-5
Molecular Formula	C8H18OS
Molecular Weight	162.29 g/mol
Synonyms	(S)-3-Methoxyheptane-1-thiol; (S)-3-Methoxy-1-heptanethiol; (1S)-3-Methoxy-1-heptanethiol; 1-Heptanethiol, 3-methoxy-, (1S)-; (S)-3-Methoxyheptyl mercaptan; Heptanethiol, 3-methoxy-, (S)-; (S)-Methoxy-3-heptanethiol; (1S)-3-Methoxyheptane-1-thiol
EINECS	Contact for details

Quality Control

Every batch of (S1)-Methoxy-3-Heptanethiol is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet your specific research or production requirements. A detailed Certificate of Analysis (COA) including chiral purity (ee%) by chiral GC or HPLC, assay, and impurity profile is supplied with each shipment. Our quality systems support development under cGMP guidelines as needed for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.