Description

Stiripentol is a structurally unique anticonvulsant agent, distinct from other major classes of antiepileptic drugs. Its primary commercial value lies in its critical role as an adjunctive therapy for the treatment of Dravet syndrome, a severe form of childhood epilepsy. This product is essential for pharmaceutical manufacturers and research institutions developing targeted therapies for refractory seizures. Stiripentol CAS NO 49763-96-4 is a key active pharmaceutical ingredient (API) requiring stringent quality control for clinical efficacy and patient safety.

Application

• Pharmaceutical API: Primary use as the active ingredient in finished dosage forms for the treatment of Dravet syndrome.
• Adjunctive Epilepsy Therapy: Used in combination with clobazam and valproate for managing refractory seizures.
• Neurological Research: A valuable compound for preclinical and clinical studies investigating mechanisms of action for GABAergic modulation.
• Drug Development: Serves as a reference standard and a key intermediate in the development of new antiepileptic formulations.
• Generic Pharmaceutical Manufacturing: Sourced by manufacturers producing generic versions of approved stiripentol medications.

Basic Information

Product Name	Stiripentol
CAS No.	49763-96-4
Molecular Formula	C14H18O3
Molecular Weight	234.29 g/mol
Synonyms	4,4-Dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-ol; (E)-4,4-Dimethyl-1-(1,3-benzodioxol-5-yl)pent-1-en-3-ol; Diacomit; BCX 2600; STP; Comitio; 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol
EINECS	256-464-5

Quality Control

Our Stiripentol is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Quality is verified through comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all test results against relevant pharmacopeial or customer specifications is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: ≤ 0.10% Total impurities: ≤ 0.50%
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.