Description

8-Chloro-2,3-Dihydro-4H-Chromen-4-One is a versatile chromenone derivative, a key heterocyclic building block prized for its unique molecular scaffold. This compound matters as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors where its structure imparts valuable biological activity. It is primarily needed by R&D chemists and process development teams in fine chemical, pharmaceutical, and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the chromenone core.
• Organic Synthesis & Material Science: Used as a versatile synthon for constructing complex heterocyclic compounds, dyes, and functional organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies, catalysis research, and exploring new chemical spaces.

Basic Information

Product Name	8-Chloro-2,3-Dihydro-4H-Chromen-4-One
CAS No.	49701-11-3
Molecular Formula	C9H7ClO2
Molecular Weight	182.60 g/mol
Synonyms	8-Chlorochroman-4-one; 8-Chloro-4-chromanone; 8-Chloro-2,3-dihydro-4H-1-benzopyran-4-one; 8-Chloro-3,4-dihydro-2H-1-benzopyran-4-one; 8-Chloro-4-chromone; 8-Chloro-4H-chromen-4-one, 2,3-dihydro-; 8-Chloro-2,3-dihydrochromen-4-one
EINECS	Contact for details

Quality Control

Our 8-Chloro-2,3-Dihydro-4H-Chromen-4-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.