Description

Hexoprenaline is a selective β-2 adrenergic receptor agonist, a high-purity pharmaceutical intermediate of significant commercial and research importance. Its primary value lies in its role as a key building block for the synthesis of advanced therapeutic agents targeting respiratory and tocolytic applications. This compound is essential for manufacturers and R&D laboratories in the global pharmaceutical and fine chemical sectors seeking reliable, high-quality active pharmaceutical ingredient (API) intermediates.

Application

• Pharmaceutical Synthesis: Primary use as a critical intermediate in the manufacture of bronchodilator and tocolytic (labor-suppressant) active pharmaceutical ingredients (APIs).
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry for developing new β-2 adrenergic agonists.
• Biochemical Studies: Used in pharmacological research to study receptor binding affinity, selectivity, and signal transduction pathways of β-adrenergic receptors.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of finished dosage forms.
• Analytical Standard: Employed as a high-purity standard in quality control laboratories for HPLC, LC-MS, and other analytical method development and validation.

Basic Information

Product Name	Hexoprenaline
CAS No.	47661-92-7
Molecular Formula	C₁₇H₂₇N₃O₅
Molecular Weight	353.41 g/mol
Synonyms	Hexoprenaline Sulfate; Ipradol; 4,4'-[1,6-Hexanediylbis(iminomethylene)]bis[1,2-benzenediol]; 1,6-Bis(3,4-dihydroxyphenyl)hexamethylenediamine; N,N'-Bis(3,4-dihydroxybenzyl)hexamethylenediamine; α,α'-[Hexamethylenebis(iminomethene)]di(3,4-dihydroxybenzyl alcohol); CAS 3215-70-1 (sulfate salt)
EINECS	Contact for details

Quality Control

Our Hexoprenaline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality assurance includes comprehensive testing against established pharmacopeial and in-house specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.