Description

4-Methyl 6-Hydroxy 7-Acetoxy Coumarin is a functionalized coumarin derivative, a versatile chemical scaffold valued for its photophysical and biological properties. This compound is a key intermediate in the synthesis of more complex molecules, particularly in the development of optical brighteners, fluorescent probes, and active pharmaceutical ingredients (APIs). It is essential for R&D laboratories and manufacturers in the fine chemical, pharmaceutical, and specialty materials sectors seeking a high-purity building block for advanced synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those leveraging the coumarin core for biological activity.
• Optical Brightener Synthesis: Used in the manufacturing of fluorescent whitening agents (FWAs) for paper, textiles, and detergents, where its structure contributes to UV absorption and blue light emission.
• Fluorescent Probe Development: Acts as a foundational component for creating sensitive fluorescent dyes and sensors used in bioimaging, diagnostics, and analytical chemistry.
• Fine Chemical Synthesis: Employed as a specialized building block in organic synthesis for creating complex heterocyclic compounds and functional materials.
• UV Absorber & Stabilizer Research: Investigated for use in polymer and coating formulations to enhance stability against photodegradation.
• Agrochemical Intermediate: Utilized in the research and development of advanced agrochemicals, such as herbicides and fungicides, based on the coumarin structure.

Basic Information

Product Name	4-Methyl 6-Hydroxy 7-Acetoxy Coumarin
CAS No.	46895-13-0
Molecular Formula	C₁₂H₁₀O₅
Molecular Weight	234.20 g/mol
Synonyms	7-Acetoxy-4-methyl-6-hydroxycoumarin; 6-Hydroxy-4-methyl-7-acetoxycoumarin; 4-Methyl-6-hydroxy-7-acetoxy-2H-chromen-2-one; 7-Acetoxy-4-methylumbelliferone; 4-Methyl-7-acetoxy-6-hydroxycoumarin; 6-Hydroxy-4-methyl-7-acetoxy-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 4-Methyl 6-Hydroxy 7-Acetoxy Coumarin is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.