Description

(S)-(-)-1,1-Diphenyl-1,2-Propanediol CAS NO 46755-94-6 is a high-purity, chiral diol compound characterized by its specific stereochemistry at the propanediol center. This compound matters as a valuable chiral building block and ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and catalysts.

Application

• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in catalytic asymmetric reactions, such as additions to carbonyl compounds.
• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of enantiomerically pure drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Catalyst Development: Used in the design and preparation of novel chiral catalysts for industrial-scale enantioselective processes.
• Agrochemical Research: Acts as a building block for chiral active ingredients in herbicides, fungicides, and insecticides.
• Material Science: Potential monomer for creating chiral polymers with specific optical properties.
• Academic & R&D: A standard reagent in university and corporate laboratories for methodological development in organic chemistry.

Basic Information

Product Name	(S)-(-)-1,1-Diphenyl-1,2-Propanediol
CAS No.	46755-94-6
Molecular Formula	C₁₅H₁₆O₂
Molecular Weight	228.29 g/mol
Synonyms	(S)-1,1-Diphenyl-1,2-ethanediol; (S)-1,1-Diphenylethane-1,2-diol; (S)-(-)-1,1-Diphenyl-2-hydroxyethanol; (S)-HOCPh2CH2OH; (S)-DPED; (S)-1,1-Diphenylglycol; (S)-α,α-Diphenyl-1,2-ethanediol; (S)-1,2-Dihydroxy-1,1-diphenylethane
EINECS	Contact for details

Quality Control

Our (S)-(-)-1,1-Diphenyl-1,2-Propanediol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.