Description

[(2R,3R,5R,6S)-2,3,4,5,6-Pentahydroxycyclohexyl]Oxyphosphonic Acid is a high-purity, stereochemically defined organophosphorus compound that serves as a critical building block and chiral intermediate in advanced chemical synthesis. Its unique structure, combining a fully substituted inositol-like cyclohexyl ring with a phosphonic acid moiety, makes it invaluable for creating molecules with specific biological activity and stereochemical integrity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise chiral scaffolds for drug discovery, catalyst development, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of nucleoside analogs, enzyme inhibitors, and other biologically active compounds targeting metabolic pathways.
• Agrochemical Research: Used in developing novel herbicides, plant growth regulators, and fungicides that act on specific enzymatic targets within plants.
• Ligand & Catalyst Synthesis: Serves as a versatile scaffold for constructing chiral ligands used in asymmetric catalysis and metal complexation.
• Biochemical Probe Development: Employed in research to create labeled analogs or inhibitors for studying phosphatases, kinases, and other phospho-transfer enzymes.
• Specialty Polymer Additive: Potential application as a monomer or additive for creating polymers with specific chelating or hydrophilic properties.
• Academic & R&D: A valuable tool for synthetic organic chemists exploring new methodologies and complex molecular architectures.

Basic Information

Product Name	[(2R,3R,5R,6S)-2,3,4,5,6-Pentahydroxycyclohexyl]Oxyphosphonic Acid
CAS No.	46495-39-0
Molecular Formula	C6H13O9P
Molecular Weight	260.14 g/mol
Synonyms	(1R,2R,3R,4R,5S)-4,5,6-Trihydroxy-2-(hydroxymethyl)cyclohexyl Dihydrogen Phosphate; 1D-myo-Inositol 1-Phosphate; myo-Inositol 1-Phosphate (1D enantiomer); (1D)-1-Phosphono-myo-inositol; Phosphoinositol; Cyclohexanol, 2,3,4,5,6-pentahydroxy-, 1-(dihydrogen phosphate), (1R,2R,3R,4R,5S)-; Inositol monophosphate (1D- isomer)
EINECS	Contact for details

Quality Control

Our [(2R,3R,5R,6S)-2,3,4,5,6-Pentahydroxycyclohexyl]Oxyphosphonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and NMR, to ensure compliance with exacting R&D and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.