Description

Benzenemethanol,A-(Aminomethyl)-4-Methoxy-,(S)- is a chiral, non-racemic organic compound featuring both benzylic alcohol and primary amine functional groups. This specific stereochemistry and bifunctional nature make it a valuable chiral building block and intermediate in asymmetric synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and fine chemical industries. The compound is essential for constructing complex molecules where precise spatial orientation is critical for biological activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for metal-catalyzed reactions, enabling the production of enantiomerically pure compounds.
• Peptidomimetic Research: Serves as a constrained amino acid analog in the design and synthesis of novel peptide-like molecules for medicinal chemistry.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials requiring specific chirality.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Item	Details
Product Name	Benzenemethanol,A-(Aminomethyl)-4-Methoxy-,(S)-
CAS No.	46084-19-9
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(S)-4-Methoxy-α-(aminomethyl)benzyl alcohol; (S)-α-(Aminomethyl)-4-methoxybenzenemethanol; L-4-Methoxy-α-(aminomethyl)benzyl alcohol; (S)-(-)-4-Methoxy-α-(aminomethyl)benzyl alcohol; (S)-1-(4-Methoxyphenyl)-2-aminoethanol; (S)-2-Amino-1-(4-methoxyphenyl)ethanol; A chiral amino alcohol derivative; Contact for additional trade names.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and each batch is analyzed to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from tests including chiral HPLC, NMR, and residual solvent analysis to ensure compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.