Description

3-Bromo-Benzo[B]Thiophen-6-Amine is a high-purity brominated heterocyclic amine building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzothiophene core.
• Material Science Research: Acts as a building block for organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs) due to its electron-rich structure.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Dye & Pigment Industry: Functions as an intermediate for synthesizing specialized dyes and pigments with unique optical properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl systems.

Basic Information

Product Name	3-Bromo-Benzo[B]Thiophen-6-Amine
CAS No.	45885-91-4
Molecular Formula	C8H6BrNS
Molecular Weight	228.11 g/mol
Synonyms	6-Amino-3-bromobenzo[b]thiophene; 3-Bromobenzo[b]thiophen-6-amine; 3-Bromo-6-aminobenzo[b]thiophene; 3-Bromo-1-benzothiophen-6-amine; 3-Bromobenzo[b]thien-6-ylamine; 3-Bromo-6-aminobenzo[b]thienyl; 3-Bromo-6-aminobenzo[b]thiophene; 3-Bromo-6-aminobenzo[b]thiophene
EINECS	Contact for details

Quality Control

Our 3-Bromo-Benzo[B]Thiophen-6-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.