Description

(4-Methoxyphenyl)-Borane is a versatile organoboron reagent featuring a borane group attached to a para-methoxyphenyl ring. This compound is a critical building block in modern synthetic organic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for drug discovery, ligand synthesis, and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that incorporate biaryl motifs for enhanced biological activity.
• Ligand & Catalyst Development: Serves as a building block for creating novel phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Chemical Research: A fundamental reagent in academic and industrial R&D for method development and exploring new chemical spaces.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, dyes, and pigments requiring specific aryl-aryl linkages.

Basic Information

Product Name	(4-Methoxyphenyl)-Borane
CAS No.	45713-46-0
Molecular Formula	C7H9BO
Molecular Weight	135.96 g/mol
Synonyms	4-Methoxyphenylboronic Acid; p-Anisylboronic Acid; (4-Methoxyphenyl)boronic Acid; 4-Methoxybenzeneboronic Acid; B-(4-Methoxyphenyl)boronic Acid; p-Methoxyphenylboronic Acid; 4-Methoxy-Benzeneboronic Acid; 4-Methoxyphenyl-Boronic Acid
EINECS	Contact for details

Quality Control

Our (4-Methoxyphenyl)-Borane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (¹H, ¹¹B, ¹³C), and titration methods, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment supports applications requiring GMP starting materials and compliance with REACH regulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.