Description

C-(1,1-Dioxo-Tetrahydro-1Lambda6-Thiophen-3-Yl)-Methylamine is a specialized sulfolane derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate, enabling the production of complex molecules with high stereochemical purity. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides that require specific stereochemistry for efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing reaction selectivity.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring a functionalized sulfolane scaffold.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	C-(1,1-Dioxo-Tetrahydro-1Lambda6-Thiophen-3-Yl)-Methylamine
CAS No.	45697-13-0
Molecular Formula	C6H11NO2S
Molecular Weight	161.22 g/mol
Synonyms	(3-Aminomethyl)tetrahydrothiophene 1,1-dioxide; 3-(Aminomethyl)tetrahydrothiophene 1,1-dioxide; 1,1-Dioxotetrahydro-3-thiophenemethanamine; 3-(Aminomethyl)thiolane 1,1-dioxide; Tetrahydro-3-thiophenemethanamine, 1,1-dioxide; 3-Aminomethylsulfolane; Sulfolane-3-methanamine
EINECS	Contact for details

Quality Control

Our C-(1,1-Dioxo-Tetrahydro-1Lambda6-Thiophen-3-Yl)-Methylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.