Description

Rac-n-Benzyl-n-[2-Hydroxyl-2-(4-Benzyloxy-3-Aminophenyl)-Ethyl]-3-(4-Methoxyphenyl)-2-Propylamine-D6 is a deuterated isotopologue of a complex benzylamine derivative, designed for advanced research and development applications. This compound is critical for studies requiring stable isotope labeling, particularly in pharmacokinetics, metabolic pathway tracing, and as an internal standard for precise analytical quantification. It serves the needs of pharmaceutical researchers, analytical chemists, and contract research organizations (CROs) engaged in the development of novel therapeutic agents and sophisticated analytical methods.

Application

• Internal Standard for Mass Spectrometry: Used as a high-purity, isotopically labeled internal standard in LC-MS and GC-MS analysis for accurate quantification of the non-deuterated parent compound in biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Enables detailed investigation of absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical and clinical research.
• Metabolic Pathway Tracing: Facilitates the elucidation of metabolic pathways and the identification of metabolites due to its isotopic signature.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and method validation in pharmaceutical manufacturing.
• Biochemical Research: Employed in mechanistic studies to understand enzyme interactions and receptor binding where isotopic labeling is beneficial.
• Chemical Synthesis Intermediate: Acts as a specialized building block for the synthesis of more complex deuterated molecules for research purposes.

Basic Information

Product Name	Rac-n-Benzyl-n-[2-Hydroxyl-2-(4-Benzyloxy-3-Aminophenyl)-Ethyl]-3-(4-Methoxyphenyl)-2-Propylamine-D6
CAS No.	43229-68-1
Molecular Formula	C31H30D6N2O3
Molecular Weight	~502.68 g/mol
Synonyms	Benzyl-[2-hydroxy-2-(4-benzyloxy-3-aminophenyl)ethyl]-[3-(4-methoxyphenyl)propyl]amine-D6; 1-(4-(Benzyloxy)-3-aminophenyl)-2-[(benzyl)(3-(4-methoxyphenyl)propyl)amino]ethanol-D6; Deuterated Benzylamine Derivative; D6-Isotopologue of (Rac)-Benzylamine Intermediate; 3-(4-Methoxyphenyl)-N-benzyl-N-[2-hydroxy-2-(4-(benzyloxy)-3-aminophenyl)ethyl]-1-propanamine-D6; [D6]-Labeled Benzyloxy Aminophenyl Ethanolamine
EINECS	Contact for details

Quality Control

Every batch of our deuterated compounds is produced and analyzed under strict quality management protocols to ensure isotopic purity and chemical integrity. Standard quality control includes verification by NMR (¹H, ¹³C) for structural confirmation and deuterium incorporation, and HPLC/UPLC for chemical purity assessment. High-Resolution Mass Spectrometry (HRMS) is used to confirm molecular formula and isotopic enrichment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere (e.g., argon or nitrogen) to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.