Description

2-Bromo (S)-Carbidopa is a key brominated derivative of the pharmaceutical intermediate (S)-Carbidopa, identified by CAS NO 43197-33-7. This compound is of significant value in advanced organic synthesis, particularly for the research and development of novel active pharmaceutical ingredients (APIs) and diagnostic agents. It serves as a critical building block for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries, enabling the exploration of new therapeutic pathways and the synthesis of complex molecular structures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel dopamine-related compounds and potential central nervous system (CNS) agents.
• Medicinal Chemistry Research: Used as a specialized building block for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Process Chemistry: Employed in route scouting and optimization for the scalable production of advanced pharmaceutical intermediates.
• Biochemical Research: Acts as a tool compound in enzymatic and receptor binding studies related to dopaminergic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, bromine-containing target molecules for client-specific R&D projects.

Basic Information

Product Name	2-Bromo (S)-Carbidopa
CAS No.	43197-33-7
Molecular Formula	C10H13BrN2O4
Molecular Weight	305.13 g/mol
Synonyms	(2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-3-bromopropanoic acid; L-α-Hydrazino-3,4-dihydroxy-α-methyl-β-(3-bromophenyl)propionic acid; (S)-2-Hydrazino-3-(3-bromo-4,5-dihydroxyphenyl)-2-methylpropanoic acid; Bromo Carbidopa; 2-Bromo Carbidopa; (S)-2-Bromocarbidopa
EINECS	Contact for details

Quality Control

Our 2-Bromo (S)-Carbidopa is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and identification by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.