Description

Pentanedioic-3,3-D2 Acid is a deuterium-labeled derivative of glutaric acid, where two hydrogen atoms at the 3-position are replaced with deuterium. This isotopic labeling makes it a crucial internal standard and tracer in advanced analytical chemistry and metabolic research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of analytical standards for applications in mass spectrometry, NMR spectroscopy, and drug metabolism studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of glutaric acid and related metabolites in complex biological matrices via GC-MS or LC-MS.
• Metabolic Pathway Tracing: Acts as a stable isotopic tracer to study the metabolism of dicarboxylic acids in vivo and in vitro.
• NMR Spectroscopy: Serves as a deuterated standard or solvent shift reference in nuclear magnetic resonance experiments.
• Pharmaceutical Research: Employed in the development and validation of bioanalytical methods for pharmacokinetic and pharmacodynamic studies.
• Manufacturing of Labeled Compounds: Used as a synthetic building block for the preparation of more complex deuterium-labeled molecules.
• Clinical Diagnostics: Potential use in assays for the detection of inborn errors of metabolism, such as glutaric aciduria.

Basic Information

Product Name	Pentanedioic-3,3-D2 Acid
CAS No.	43087-19-0
Molecular Formula	C5H6D2O4
Molecular Weight	134.13 g/mol
Synonyms	Glutaric-3,3-d2 Acid; 3,3-Dideuterioglutaric Acid; [3,3-2H2]Glutaric Acid; 1,5-Pentanedioic-3,3-d2 Acid; Deuterated Glutaric Acid; Pentanedioic Acid-3,3-d2; 3,3-Dideuteropentanedioic Acid
EINECS	Contact for details

Quality Control

Our Pentanedioic-3,3-D2 Acid is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D atom%), chemical purity, and impurity profile. We adhere to rigorous quality testing protocols to guarantee batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.