Description

Umckalin is a high-purity, naturally derived benzopyranoquinoline alkaloid, recognized for its significant biological activity and research interest. This compound is valued for its role as a key reference standard and active pharmaceutical ingredient (API) in the development of therapeutic formulations. It is primarily sought by manufacturers and research institutions in the pharmaceutical, nutraceutical, and advanced life science sectors for applications in respiratory health and immune support products.

Application

• As a reference standard for analytical method development and quality control in pharmaceutical laboratories.
• As an active pharmaceutical ingredient (API) in the formulation of herbal medicinal products and dietary supplements targeting respiratory wellness.
• In preclinical and clinical research to study mechanisms of action related to immune modulation and antimicrobial activity.
• For the standardization of herbal extracts, particularly those derived from *Pelargonium sidoides*, to ensure batch-to-batch consistency and potency.
• As a key intermediate in the synthesis of novel derivatives for structure-activity relationship (SAR) studies in drug discovery programs.

Basic Information

Product Name	Umckalin
CAS No.	43053-62-9
Molecular Formula	C₁₉H₂₂O₄
Molecular Weight	314.38 g/mol
Synonyms	7-Hydroxy-5,6-dimethoxy-2-methyl-2-(4-methylpent-3-en-1-yl)-2H-1-benzopyran-8-carbaldehyde; 7-Hydroxy-5,6-dimethoxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-8-carboxaldehyde; 2H-1-Benzopyran-8-carboxaldehyde, 7-hydroxy-5,6-dimethoxy-2-methyl-2-(4-methyl-3-pentenyl)-; Umckalin (from Pelargonium sidoides)
EINECS	Contact for details

Quality Control

Our Umckalin is produced under strict quality management systems to ensure it meets the high standards required for pharmaceutical and research use. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via validated methods such as HPLC and MS. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.