Description

[(4,4-Dimethylcholest-5-En-3β-Yl)Oxy]Trimethylsilane is a high-purity, organosilicon-modified sterol derivative, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in providing a protected hydroxyl group on the sterol backbone, enabling precise chemical modifications for research and development. This compound is essential for pharmaceutical chemists and R&D laboratories focused on developing novel steroid-based therapeutics, bioactive molecules, and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a protected precursor for studying sterol metabolism, receptor interactions, and signal transduction pathways.
• Fine Chemical Synthesis: Intermediate in the production of specialized surfactants, liquid crystals, and other high-performance materials derived from sterol chemistry.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid analysis.

Basic Information

Product Name	[(4,4-Dimethylcholest-5-En-3β-Yl)Oxy]Trimethylsilane
CAS No.	42995-75-5
Molecular Formula	C32H58OSi
Molecular Weight	486.89 g/mol
Synonyms	3β-[(Trimethylsilyl)oxy]-4,4-dimethylcholest-5-ene; 4,4-Dimethylcholest-5-en-3β-ol trimethylsilyl ether; Cholest-5-ene-3β-ol, 4,4-dimethyl-, 3-trimethylsilyl ether; 4,4-Dimethyl-5-cholesten-3β-yloxytrimethylsilane; TMS ether of 4,4-dimethylcholest-5-en-3β-ol; Trimethyl(4,4-dimethyl-5-cholesten-3β-yloxy)silane
EINECS	Contact for details

Quality Control

Our [(4,4-Dimethylcholest-5-En-3β-Yl)Oxy]Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.