Description

(4-Carboxybutyl-2,2,3,3-D4)Triphenylphosphonium Bromide is a high-purity, isotopically labeled organophosphorus compound, specifically a deuterated Wittig reagent salt. This product is essential for advanced research and development, offering a stable isotopic label for precise mechanistic studies and analytical method development. It is primarily needed by scientists and manufacturers in the pharmaceutical, agrochemical, and academic research sectors, particularly for applications in organic synthesis, metabolic pathway tracing, and as a critical standard in mass spectrometry.

Application

• Deuterium-Labeled Synthetic Intermediate: Used in the synthesis of deuterium-labeled organic molecules, including pharmaceuticals and fine chemicals, for metabolic and pharmacokinetic studies.
• Wittig Reaction Reagent: Acts as a specialized Wittig reagent for the stereoselective synthesis of alkenes with deuterium-labeled side chains.
• Internal Standard for Mass Spectrometry: Serves as a high-purity quantitative internal standard in LC-MS and GC-MS analyses to ensure accuracy in bioanalytical and environmental testing.
• Mechanistic Probe in Organic Chemistry: Employed in reaction mechanism elucidation and isotope effect studies due to its stable deuterium atoms.
• Precursor for Labeled Biomolecules: Used in the preparation of deuterated analogs of fatty acids, lipids, and other biologically active compounds.
• Research & Development: Critical for R&D in drug discovery, where isotopic labeling is required for patent protection, regulatory filings, and advanced material science.

Basic Information

Item	Detail
Product Name	(4-Carboxybutyl-2,2,3,3-D4)Triphenylphosphonium Bromide
CAS No.	42932-63-8
Molecular Formula	C23H20D4BrO2P
Molecular Weight	447.33 g/mol (for deuterated form)
Synonyms	5-(Triphenylphosphonio)pentanoate-2,2,3,3-d4 bromide; [5-(Triphenyl-λ5-phosphanyl)pentanoic-2,2,3,3-d4 acid] bromide; Deuterated Triphenyl(5-carboxypentyl)phosphonium bromide; (5-Carboxypentyl-2,2,3,3-d4)triphenylphosphonium bromide; ω-Carboxybutyl-2,2,3,3-d4 triphenylphosphonium bromide; D4-Labeled Wittig Salt; 42932-63-8 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our (4-Carboxybutyl-2,2,3,3-D4)Triphenylphosphonium Bromide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, isotopic enrichment, and identity. Certificates of Analysis (COA) are provided, detailing results for assay, deuterium incorporation, and impurity profiles via techniques such as NMR and HPLC. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions, ideally in a desiccator. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.